Cognitive and renal dysfunction in the elderly

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Cognitive and renal dysfunction in the elderly

Cognitive impairment has been associated with several diseases and organic disturbances but few studies have explored the relationship between renal function and cognition. OBJECTIVE The aim of this study was to compare the renal function of elderly patients with and without Alzheimer's disease, and to identify potential associated comorbidities, as well as the presence of microalbuminuria. ...

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Benzodiazepines and postoperative cognitive dysfunction in the elderly. ISPOCD Group. International Study of Postoperative Cognitive Dysfunction.

Postoperative cognitive dysfunction (POCD) has been attributed to long-acting sedatives. We hypothesized that diazepam and its active metabolites could be detected in blood after surgery and correlated with POCD, 1 week after surgery in elderly patients. We studied 35 patients, 60 yr or older, undergoing abdominal surgery with general anaesthesia, including diazepam. Neuropsychological tests we...

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The Rate of Antibiotic Dosage Adjustment in Renal Dysfunction

The purpose of this study was to determine the number of prescribed antibiotics being appropriately adjusted and to assess antibiotics with the highest incorrect dosing based on the patient’s renal function according to distinguished guidelines. The study was conducted at a 446-bed university hospital. One hundred and fifty patients admitted through different wards of the hospital were included...

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The Rate of Antibiotic Dosage Adjustment in Renal Dysfunction

The purpose of this study was to determine the number of prescribed antibiotics being appropriately adjusted and to assess antibiotics with the highest incorrect dosing based on the patient’s renal function according to distinguished guidelines. The study was conducted at a 446-bed university hospital. One hundred and fifty patients admitted through different wards of the hospital were included...

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Cognitive dysfunction after minor surgery in the elderly.

BACKGROUND Major surgery is frequently associated with postoperative cognitive dysfunction (POCD) in elderly patients. Type of surgery and hospitalization may be important prognostic factors. The aims of the study were to find the incidence and risk factors for POCD in elderly patients undergoing minor surgery. METHODS We enrolled 372 patients aged greater than 60 years scheduled for minor su...

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ژورنال

عنوان ژورنال: Dementia & Neuropsychologia

سال: 2013

ISSN: 1980-5764

DOI: 10.1590/s1980-57642013dn74000007